Mysqli statement execute error : Prepared statement needs to be re-prepared

i get permanent this error:

Mysqli statement execute error : Prepared statement needs to be re-prepared

whats wrong? is it the server? or the database?

A prepared statement has to be reprepared after a DDL operation. Automatic statement repreparation is only available as of MySQL 5.1.25. You should use the PDO adapter if possible.

i use MySQL-Client-Version: 5.1.37
what is a PDO adapter?

Do you have a backtrace showing where this is coming from?