Display all messed up

up until this afternoon Piwik was working fine then sudenly the page display is all messed up (see screenshot), it is happening Firefox, IE and Chrome, I’ve tried refreshing the page, clearing the browser cache but all to no avail.

The only change made to the server was an update to ISPConfig 3 and I don’t see why that should have messed up PiWik

Anyone have a clue as to what may be happening here?